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Androgenetic Alopecia: Features, Causes, and Remedies

Androgenetic alopecia is a common form of baldness characterized by progressive hair thinning, resulting from a process of miniaturization that ultimately leads to the involution of hair follicles. Throughout life, it affects approximately 80% of the male and 50% of the female populations. The prevalence of androgenetic alopecia is such that it can be considered a physiological condition. Yet, it is often experienced as profound discomfort, with numerous psychological and social repercussions, especially for women and young individuals. Let's delve into it further.

What are the differences between male and female androgenetic alopecia?

The progression of androgenetic alopecia is gradual; however, it manifests variably based on gender:

Male alopecia or male pattern baldness is one of the most common manifestations of androgenetic alopecia. It usually begins with a “receding hairline,” characterized by hair loss in the frontal area of the scalp. Over time, this loss can extend to the top of the head, creating the well-known “crown baldness” effect. In more advanced cases, hair may be further thin, leaving only a narrow crown of hair around the sides and back of the head.

Male alopecia is often associated with an excessive presence of dihydrotestosterone (DHT) in the hair follicles. DHT is an active form of testosterone, a male hormone that accelerates the hair growth phase, making it thinner and shorter. Over time, this shortened growth phase leads to follicle degeneration and permanent hair loss.


In women, hair loss is generally less noticeable initially and often involves diffuse thinning across the entire scalp. It is uncommon for women to develop a pronounced receding hairline or crown baldness like men. Instead, women with androgenetic alopecia may notice a gradual thinning of hair across the entire head.

This form of alopecia is often associated with a relative increase in “male hormones” in women. For example, in the post-menopausal phase, the cessation of ovarian synthesis of estrogen hormones, known as “female hormones,” can increase androgens. This rise in androgens can negatively impact the growth phase, triggering hair thinning.


When does androgenetic alopecia manifest?

The condition can begin as early as adolescence, and the likelihood of experiencing it increases over time. The fact that androgenetic alopecia can start at a young age and is influenced by genetic predisposition makes this condition a significant part of the natural evolution of many individuals. However, it is essential to emphasize that this situation can be perceived as very stressful and have negative psychological and social repercussions.

In individuals where androgenetic alopecia starts at an earlier age, the progression can be faster. Additionally, in men, androgenetic alopecia is often associated with hereditary factors. The name itself suggests its origin and is linked to genetic predisposition and an excessive response to androgens, the male hormones.

What are the causes of androgenetic alopecia?

  • The causes of androgenetic alopecia result from a combination of genetic predisposition and an excess of male hormones, particularly DHT (dihydrotestosterone). In individuals affected by this condition, there is a significant increase in DHT levels in the hair follicles due to the heightened activity of the enzyme 5α-reductase type II, a protein that converts testosterone into DHT.

    DHT accelerates the hair growth phase, but incompletely, producing thin and short hairs known as “vellus hairs.”
     Over time, these vellus hairs may disappear, leading to the involution of follicles and hair loss.

  • In women, this condition can be a manifestation of ovarian or adrenal endocrinological disorders. The effect of menopause, which involves the cessation of ovarian synthesis of estrogens and a relative increase in androgens, can contribute to hair thinning.

  • Some pharmacological therapies can negatively impact hair growth. For example, oral contraceptives containing a progestin hormone with androgenic activity can lead to hair thinning through mechanisms similar to those of androgenetic alopecia. Similarly, the use of anabolic steroids can have similar effects on hair health.

Discover CRLAB solutions for a comprehensive and effective approach to hair loss

Trichological treatments can be valuable allies against androgenetic alopecia, especially in the early stages, as they halt hair loss and improve the quality and thickness of the hair. The use of specially formulated products, combined with the latest technologies, constitutes one of the primary responses when experiencing particularly intense or abnormal hair loss.

At CRLAB, we complement topical treatments and products with dietary supplements, which can play a significant role in the prevention and treatment of androgenetic alopecia. These products complement CRLAB trichological lines, providing an additional contribution.

Women’s Hair

Women’s Hair – Pygeum Africanum and Omega-3 counteract hair loss by inhibiting the enzyme alpha-5-reductase. This enzyme is responsible for converting testosterone into DHT, a hormone that negatively influences the productive activity of hair follicles. Green tea has an anti-inflammatory effect, while a boost of vitamins and minerals promotes hair regrowth.

The supplement can accompany the Anti-Hair Loss Green Line for a comprehensive treatment.

Men’s Hair

Men’s Hair – The action of Serenoa Repens inhibits the enzyme alpha-5-reductase, which is responsible for the miniaturization and shedding of hair. Biotin stimulates hair follicles and deeply nourishes hair, making it stronger, softer, and shinier. The targeted action of vitamins, minerals, and amino acids gives the hair a thicker appearance. A synergistic approach with the Anti-Hair Loss Green Line is recommended.

Discover the entire Supplement Line.

The CRLAB Hair Thickening System: a Non-Invasive Solution to Provide a Concrete Answer to Androgenetic Alopecia

In the case of CRLAB, a completely personalized prosthetic system has been conceived and patented to meet the needs of men and women with various degrees of baldness or thinning hair who want to regain self-confidence.

This innovative, effective, non-invasive solution comprises a biocompatible polymeric base onto which natural and virgin hairs are manually grafted. The implant adheres to the head thanks to medical-grade adhesives (in this article,we have outlined the main advantages of the CRLAB system compared to less personalized solutions).

Do you also want to rediscover the dream hair you've always desired?

Take the first step toward your new smile and book a consultation at the nearest CRLAB center now.